The imaging of hippocampal amyloid is ... in more recent human and mouse studies, neuronal dysfunction in AD is related to regional levels of soluble Aβ, not fully formed plaques.

This is what a neuron from the hippocampus of a rat looks like. The cell and it's extensive processes are visualized using a fluorescent dye, filled via a glass pipette. The glass pipette ...

While all three genotypes of mice performed similarly to wild-type animals on multiple behavioral and spatial memory tests, they faltered in tests of working memory. APP-KI had a subtle deficit, which ...

Using a combined experimental-theoretical approach unique in neuroscience, the authors present important techniques for the physiological reconstruction of a large biological neuronal network. They ...