During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

随后研究团队研究发现抑制RF-RDs会导致复制叉新生DNA的降解，并显著增加DNA末端切割和DNA断裂的发生。进一步体外生化实验和细胞实验表明，RF-RDs能够抑制核酸酶DNA2的核酸酶活性，从而减缓DNA2对复制叉的降解。研究团队进一步通过全基因组 ...

Inc. Report Highlights Key Drivers, Trends, and Opportunities Shaping Market GrowthWilmington, Delaware, Inc. –, Dec. 10, ...

Market OverviewDNA polymerases catalyze the synthesis of DNA molecules from nucleoside triphosphates, ensuring the accurate ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.

As there are currently no treatments for BKPyV, infection can cause graft loss. With only seven genes, BKPyV relies on its ...

The study is published in the journal PLOS Pathogens. With only seven genes, the BK polyomavirus must use the host cell’s DNA replication machinery to produce new viruses. Although the virus was ...

Researchers reveal new findings on BK polyomavirus replication, offering potential drug targets to protect kidney transplants ...

as well as for DNA replication, repair, and segregation to daughter cells. Nucleosomes are repetitive building blocks ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...