环形 RNA(circular RNA,circRNA)是一类广泛存在于真核细胞中的内源性非编码 RNA 分子,在生物体发育过程中发挥着重要作用。其独特的环状结构使其免 ...
近日,中国科学院广州生物医药与健康研究院(广州健康院)冯立强研究员、巫林平研究员与广州实验室陈凌研究员等合作,在Nature Communications期刊发表了题为“A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice”的最新研究成果 ...
The company launched its first product, MindLight, in September 2024. MindLight uses the company’s circular-RNA (circRNA) platform to predict the patients who are more likely to respond to the ...
m6A是mRNA和lncRNA上含量最丰富的修饰,在转录后各个水平影响mRNA/lncRNA 的代谢和功能 [1]。此外,m6A还参与了其它ncRNA的功能,例如,调控circRNA非帽子依赖的翻译起始[2]和pri-miRNA的成熟过程[3]。 RNA修饰的潜在功能不仅取决于其所修饰的是何种基因转录本,同时也 ...
SINGAPORE – A vaccine for the Nipah virus could be on the horizon, thanks to research on a new vaccine technology. Vaccine research organisation Hilleman Laboratories has announced a ...